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    Cholesterol FAQs, News and Awareness Video
    "Factors That Make Cholesterol High Or Low"
    Benefits For A Healthy Heart

    Cholesterol Awareness Video

    What Is Cholesterol?

    Cholesterol is a waxy substance that occurs naturally in all parts of the body and is necessary for the body to function normally. The body uses cholesterol to produce many hormones, vitamin D, and bile acids that help digest fat. Only a small amount of cholesterol is needed to meet these needs. Excess cholesterol in the bloodstream can be harmful and lead to arteriosclerosis, a condition in which fat and cholesterol are deposited in the walls of the arteries, including the coronary arteries feeding the heart.
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    Latest Cholesterol News
    Gene tied to muscle weakness from cholesterol drugs (San Diego Union-Tribune)
    BOSTON – British researchers have located a gene responsible for muscle pain or weakness experienced by some people taking statin drugs to fight “bad” cholesterol, they reported Wednesday.

    Intensified concerns on the cholesterol drug Vytorin (International Herald Tribune)
    The cholesterol-lowering drug Vytorin did not help people with heart-valve disease avoid further heart problems but did appear to increase their risk of cancer, scientists reported Monday.

    Cholesterol Study Sinks Drug Makers' Stocks (NPR)
    A study released Monday of adults with heart disease found no evidence that using cholesterol drugs Vytorin and Zetia lowers heart-valve disease. The study's results sent shares of the companies that make the drugs tumbling.

    Merck withholds forecasts after cholesterol study (Reuters via Yahoo! News)
    Merck & Co Inc cut its sales outlook on two key medicines on Monday and indicated its financial forecasts were in doubt after a mostly negative study of cholesterol treatment Vytorin, sending its shares down 7 percent.

    Cholesterol drug Vytorin fails new trial / Schering-Plough, Merck shares sink on heart valve study results (San Francisco Chronicle)
    In the latest disappointment for cholesterol pill Vytorin, a major European study in patients with heart valve disease found the drug didn't prevent worsening of the disease or lower the need for valve surgery, sending its makers' stock plunging. Results of a...

    Cholesterol drug faulted in study (Baltimore Sun)
    TRENTON, N.J. In the latest disappointment for the cholesterol pill Vytorin, a major European study in patients with heart valve disease found the drug didn't prevent worsening of the disease or lower the need for valve surgery. Results of a preliminary analysis of the just-completed study showed Vytorin, marketed jointly by Merck & Co. and Schering-Plough Corp., was no better than placebo at ...

    Cholesterol Drug Fails Cardio Test (CBS News)
    Schering-Plough Corp. and Merck & Co.'s cholesterol drug Vytorin doesn't lower the risk of major heart valve problems and the need for related surgical procedures, according to a large-scale study.

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    In time, the arteries narrow and symptoms of CHD appear, including angina and heart attacks. It is currently recommended that your total cholesterol level be less than 200mg/dl. Some new guidelines consider cholesterol levels of no more than 180 to be optimal.

    Cholesterol travels in the blood in packages called lipoproteins. Low Density Lipoproteins (LDL) are the bad cholesterol since they carry most of the cholesterol in the blood which is the main source of buildup that damages and blocks the arteries. The more LDL-cholesterol you have, the greater the risk of CHD. If your LDL is higher than 130mg/dl, your cholesterol is probably too high.

    High Density Lipoproteins (HDLs) are the good cholesterol, as they carry cholesterol in the blood from other parts in the body to the liver, which leads to removal of cholesterol from the body. HDLs help cholesterol from building up in the arterial walls. If your level of HDL-cholesterol is below 35mg/dl, you are at risk for CHD. The higher your HDL-cholesterol the better. The average HDL-cholesterol for men is about 45 mg/dl, and for women 55 mg/dl.

    Triglycerides are a form of fat carried in the bloodstream. Most of your bodys fat in the form of triglycerides is stored in fat tissue. Only a small segment of triglycerides is in the bloodstream. High triglyceride levels alone do not cause atherosclerosis. However, lipoproteins that are rich in triglycerides also contain cholesterol, which causes atherosclerosis in some people with high triglycerides.

    What are the factors that make cholesterol high or low?

    Heredity plays a large role in determining your LDL cholesterol levels. One form of inherited high cholesterol affects 1 in 500 people. It is called familial hyercholesterolemia, and often leads to early CHD.

    Diets high in saturated fat, mainly from foods that come from animals, often cause of LDL-cholesterol levels to increase. Reducing the amount of saturated fat in your diet is a significant step in reducing blood cholesterol levels.

    Weight, in excess, tends to increase LDL-cholesterol levels. If you are overweight (please refer to the Body Mass Calculator to determine your ideal body weight) losing weight may help lower triglycerides and raise HDL.

    Age affects LDL-cholesterol levels, especially in women. Prior to menopause, women most often have lower cholesterol levels than men of the same age. As women age, their blood cholesterol levels rise until about the age of 60 to 65. Menopause often increases LDL-cholesterol and decreases HDL-cholesterol. After the age of 50, women generally have higher total cholesterol levels than men of the same age.

    Alcohol intake increases HDL- cholesterol but does not decrease LDL-cholesterol. While drinking in moderation may help, too much alcohol can damage the liver, heart muscle, increase blood pressure, and raise triglycerides.

    Stress has been shown to raise blood cholesterol levels. Many times, people under pressure console themselves by eating fatty foods. The saturated fat and cholesterol in these foods contribute to high LDL levels (Please read about the benefits of the nutritional Cholesterol Formula herbal for a healthy heart).

    References: Garg R, Malinow M, Pettinger M, Upson B, Hunninghake D. Niacin treatment increases plasma Ghomocyst(e)ine levels. Am Heart J ;138:1082-7, 1999.

    Goldberg A, Alagona P Jr, Capuzzi DM, et al. Multiple-dose efficacy and safety of an extended-release form of niacin in the management of hyperlipidemia. Am J Cardio; 85:1100-5., 2000.

    Malhotra SC, Ahuja MMS, Sundarum KR. Long-term clinical studies on the hypolipidemic effect of Commiphora mukul (guggul) and clofibrate. Ind J Med Res; 65:390-95, 1977.

    Mattson, F. et al. Optimizing the effect of plant sterols on cholesterol absorption in man. Am. J. Clin. Nutr. 35:697-700, 1982.

    Mester L, Mester M, Nityanand S. Inhibition of platelet aggregation by guggulu steroids. Planta Med; 37:367-69, 1979.


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